Document Detail

Intima-media thickness of the abdominal aorta of neonate with different gestational ages.
MedLine Citation:
PMID:  17436319     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine aortic intima-media thickness (aIMT) values in newborns with different gestational ages and to asses the effect of antenatal steroids on aIMT. METHODS: Two hundred forty newborns from healthy mothers had their distal abdominal aIMT measured during abdominal sonographic examination. The neonates were divided into 4 groups (60 in each group) according to gestational age: group I (25-28 weeks), group II (29-32 weeks), group III (33-37 weeks), and group IV (38-42 weeks). RESULTS: The interobserver and intersubject intraclass correlation coefficient was 0.93 and 0.94, respectively. Mean aIMT was 0.316 mm, 0.335 mm, 0.348 mm, and 0.385 mm, respectively, in group I, II, III, and IV, increasing significantly with gestational age at birth (p < 0.0001). There was no apparent effect of antenatal steroid use on aIMT. Multivariate regression models for mean aIMT demonstrated a significant association with aortic lumen diameter (p < 0.0001). CONCLUSION: Abdominal aIMT can be reproducibly measured in neonates and may be a useful tool for epidemiologic studies.
Esad Koklu; Selim Kurtoglu; Mustafa Akcakus; Ali Yikilmaz; Abdulhakim Coskun; Tamer Gunes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  35     ISSN:  0091-2751     ISO Abbreviation:  J Clin Ultrasound     Publication Date:    2007 Nov-Dec
Date Detail:
Created Date:  2007-10-10     Completed Date:  2008-01-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  491-7     Citation Subset:  IM    
Copyright Information:
(c) 2007 Wiley Periodicals, Inc.
Division of Neonatology, Department of Pediatrics, Erciyes University, School of Medicine, 38039 Kayseri, Turkey.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Aorta, Abdominal / drug effects,  ultrasonography*
Birth Weight
Blood Pressure / physiology
Body Height
Gestational Age*
Infant, Newborn*
Maternal Age
Sex Factors
Tunica Intima / drug effects,  ultrasonography*
Tunica Media / drug effects,  ultrasonography*
Reg. No./Substance:
0/Adrenal Cortex Hormones

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