Document Detail

Intestinal uptake of (99m)Tc-MDP: a case report of protein-losing enteropathy correlated with pathology findings from autopsy.
MedLine Citation:
PMID:  21110145     Owner:  NLM     Status:  In-Data-Review    
We present a case of a 60-year-old man with a history of severe hypoproteinemia and constitutional syndrome, suspected to have protein-losing enteropathy (PLE). Bone scintigraphy ((99m)Tc-MDP) performed to rule out the presence of bone metastases incidentally showed abnormal uptake in abdominal soft tissue. The patient unexpectedly died of heart failure, and autopsy revealed microscopic alterations consistent with PLE exclusively in the right colon, corresponding to the area of abnormal uptake. Few similar cases have been published, but none of them reported correlative pathological findings affecting the area of abnormal tracer uptake. In this case of PLE, (99m)Tc-MDP scintigraphy was a useful imaging method for localizing the site of protein loss, showing a focal area of alteration in the right colon. This finding could also have been of great help in case that surgery had been finally performed to control the protein loss.
Begoña Martinez-Sanchis; Virginia Cortés-Vizcaíno; Lorena Frontado-Morales; Pablo Sopena-Novales
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Publication Detail:
Type:  Journal Article     Date:  2010-11-26
Journal Detail:
Title:  Annals of nuclear medicine     Volume:  25     ISSN:  1864-6433     ISO Abbreviation:  Ann Nucl Med     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8913398     Medline TA:  Ann Nucl Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  139-41     Citation Subset:  IM    
Nuclear Medicine Department, Hospital Dr. Peset, Avda. Gaspar Aguilar, 90, 46017, Valencia, Spain,
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