Document Detail

Intestinal type adenocarcinoma of the ethmoid sinus in wood and leather workers: A retrospective study of 153 cases.
MedLine Citation:
PMID:  20665741     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: The purpose of our study was to identify the role of work exposure to organic dusts in patients with malignant paranasal sinus tumors.
METHODS: We analyzed all patients surgically treated for a malignant paranasal sinus tumor at our institution between 1987 and 2006. All patients were specifically asked about their occupational history. The tumor site was classified as maxillary or ethmoid sinus. Adenocarcinomas were divided into intestinal type (ITAC) and non-ITAC.
RESULTS: The sample included 345 patients with ethmoid sinus and 301 maxillary sinus. Regarding the ethmoid sinus, we found an exposure to organic dusts in 148 of 153 patients with ITAC, in 3 of 16 patients with non-ITAC adenocarcinoma, and in 10 of 176 patients with other tumors. Regarding the maxillary sinus, we found an exposure in 1 of 20 patients with non-ITAC adenocarcinoma and in 4 of 281 patients with other histologies.
CONCLUSION: Our study demonstrates that only ethmoid ITACs have an indisputable relationship with the exposure to organic dusts. © 2010 Wiley Periodicals, Inc. Head Neck, 2011.
Giulio Cantu; Carlo L Solero; Luigi Mariani; Salvatore Lo Vullo; Stefano Riccio; Sarah Colombo; Madia Pompilio; Federica Perrone; Paolo Formillo; Pasquale Quattrone
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Head & neck     Volume:  33     ISSN:  1097-0347     ISO Abbreviation:  Head Neck     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  United States    
Other Details:
Languages:  eng     Pagination:  535-42     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Wiley Periodicals, Inc.
Cranio-Maxillo-Facial Unit, Fondazione I.R.C.C.S. Istituto Nazionale dei Tumori, Milan, Italy.
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