Document Detail


Intestinal radiocalcium absorption in the goat: measurement by a double-isotope technique.
MedLine Citation:
PMID:  6546295     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intestinal radiocalcium absorption was measured in goats by a double-isotope technique involving injection of 45CaCl2 intravenously and 47CaCl2 into the abomasum. Cumulative absorption of radiocalcium was calculated by deconvolution analysis form curves of plasma radioactivity. Repeated measurements at 2 d intervals gave highly reproducible results (r 0.94, P less than 0.001). No systematic difference between two consecutive measurements was observed. A good agreement between absorption of radiocalcium from simultaneously administered 47CaCl2 and 45Ca-labelled hay (r 0.93, P less than 0.001) seems to justify the use of inorganic 47Ca as a tracer for Ca in ruminant diets. Two- to three-fold increases in radiocalcium absorption 48 h after oral treatment with 1,25-dihydroxycholecalciferol or leaves of Solanum malacoxylon showed the usefulness of the method in situations of rapidly changing Ca absorption. Endogenous adaptations in intestinal radiocalcium absorption from 20 to 43% were observed in lactating goats when Ca intakes decreased from 12 to 4 g/d. It is concluded that the double-isotope technique is a suitable method for studies of Ca absorption in ruminants when tracer is introduced into the abomasum. The test is completed in 3-4 h and may therefore be used in situations where the absorption of Ca undergoes rapid changes.
Authors:
K Hove
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The British journal of nutrition     Volume:  51     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-02-24     Completed Date:  1984-02-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  145-56     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Calcitriol / pharmacology
Calcium / metabolism*
Calcium Radioisotopes / diagnostic use*
Calcium, Dietary / administration & dosage
Female
Goats / metabolism*
Intestinal Absorption* / drug effects
Lactation
Methods
Plants, Edible
Pregnancy
Time Factors
Chemical
Reg. No./Substance:
0/Calcium Radioisotopes; 0/Calcium, Dietary; 32222-06-3/Calcitriol; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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