| Intestinal pseudo-obstruction following the use of enteral charcoal and sorbitol and mechanical ventilation with papaveretum sedation for theophylline poisoning. | |
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MedLine Citation:
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PMID: 1536699 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report 2 cases of intestinal pseudo-obstruction, 1 fatal, which developed following the use of enteral activated charcoal with sorbitol, and mechanical ventilation with papaveretum ('Omnopon') sedation for the treatment of severe theophylline self-poisoning. While mechanical intestinal obstruction may rarely complicate the use of enteral activated charcoal, pseudo-obstruction has not been previously described. Causal mechanisms and prophylaxis are discussed, highlighting a possible interaction between theophylline and papaveretum, and the dangers of multidose enteral charcoal with sorbitol in this context. |
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Authors:
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P Longdon; A Henderson |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Drug safety : an international journal of medical toxicology and drug experience Volume: 7 ISSN: 0114-5916 ISO Abbreviation: Drug Saf Publication Date: 1992 Jan-Feb |
Date Detail:
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Created Date: 1992-04-02 Completed Date: 1992-04-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9002928 Medline TA: Drug Saf Country: NEW ZEALAND |
Other Details:
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Languages: eng Pagination: 74-7 Citation Subset: IM |
Affiliation:
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Intensive Care Unit, Princess Alexandra Hospital, Brisbane, Queensland, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Charcoal / adverse effects*, therapeutic use Drug Interactions Enteral Nutrition Humans Intestinal Obstruction / etiology* Male Middle Aged Opium / therapeutic use* Sorbitol / adverse effects*, therapeutic use Theophylline / poisoning* Ventilators, Mechanical* |
| Chemical | |
Reg. No./Substance:
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16291-96-6/Charcoal; 50-70-4/Sorbitol; 58-55-9/Theophylline; 8008-60-4/Opium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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