Document Detail

Intestinal permeability to 51Cr-labelled ethylenediaminetetraacetate in food-intolerant subjects.
MedLine Citation:
PMID:  2504639     Owner:  NLM     Status:  MEDLINE    
Intestinal permeation of 51Cr-labelled ethylenediaminetetraacetate (51Cr-EDTA) was normal in 8 food-intolerant patients. Following ingestion of the offending food stuff there was a significant (p less than 0.003) decrease in the permeation of 51Cr-EDTA but the same phenomenon was observed in control subjects (n = 5) following cereal. Eight patients were tested following ingestion of lentil puree and subsequently with lentil puree containing the food to which they were sensitive. In these patients there was a significant increase in the permeation of 51Cr-EDTA following the 2nd test (p less than 0.01), but this was of insufficient magnitude to be of diagnostic use. These results show that food intolerance does involve some, but not gross changes in intestinal permeability to 51Cr-EDTA.
G Scadding; I Bjarnason; J Brostoff; A J Levi; T J Peters
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Digestion     Volume:  42     ISSN:  0012-2823     ISO Abbreviation:  Digestion     Publication Date:  1989  
Date Detail:
Created Date:  1989-09-29     Completed Date:  1989-09-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  104-9     Citation Subset:  IM    
Department of Immunology, Middlesex Hospital Medical School, London, UK.
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MeSH Terms
Chromium Radioisotopes / diagnostic use
Edetic Acid / diagnostic use
Food Hypersensitivity / diagnosis,  etiology*
Intestinal Absorption*
Middle Aged
Reg. No./Substance:
0/Chromium Radioisotopes; 60-00-4/Edetic Acid

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