Document Detail

Intestinal obstruction in pregnancy by ondansetron.
MedLine Citation:
PMID:  25461913     Owner:  NLM     Status:  Publisher    
BACKGROUND: Ondansetron use for nausea and vomiting during pregnancy has increased in the last years, although its maternal and fetal safety is not conclusive.
CASE: We describe a case of intestinal obstruction in a pregnant woman with severe nausea and vomiting of pregnancy treated with ondansetron, which is known to slow gut motility.
CONCLUSION: The spontaneous reporting system of WHO confirms that this potentially life threatening complication is more common than what the peer review literature may suggest and needs to be looked into carefully, especially in view of the wide spread off-label use for NVP.
Rana Cohen; Meital Shlomo; Dorit Nahlieli Dil; Natalia Dinavitser; Mati Berkovitch; Gideon Koren
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-10-24
Journal Detail:
Title:  Reproductive toxicology (Elmsford, N.Y.)     Volume:  50C     ISSN:  1873-1708     ISO Abbreviation:  Reprod. Toxicol.     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-12-2     Completed Date:  -     Revised Date:  2014-12-3    
Medline Journal Info:
Nlm Unique ID:  8803591     Medline TA:  Reprod Toxicol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  152-153     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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