| Intestinal development and fatty acid binding protein activity of newborn pigs fed colostrum or milk. | |
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MedLine Citation:
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PMID: 1420614 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Newborn pigs (n = 20) were gavage-fed sow's colostrum, defatted colostrum, milk, defatted milk or a 5% lactose solution over 24 h in order to evaluate effects on growth and functional differentiation of small intestine. Colostrum-fed pigs had greater (p less than 0.01) mucosal mass in the proximal half of the small intestine than did the milk- or lactose-fed groups. Total fatty acid binding protein (FABP) activity and FABP activity per mg DNA in proximal intestines of colostrum-fed pigs exceeded that for the lactose group. FABP activities (per g mucosa or mg soluble protein) were greater (p less than 0.01) in the proximal segments of small intestines of pigs fed whole versus the corresponding defatted secretion. These results indicate that the feeding of colostrum specifically augments perinatal intestinal growth and differentiation as manifested by increased cellular hypertrophy and FABP activity. Milk lipid and unidentified factor(s) enriched in colostrum are inducers of intestinal FABP activity. |
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Authors:
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G A Reinhart; F A Simmen; D C Mahan; M E White; K L Roehrig |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Biology of the neonate Volume: 62 ISSN: 0006-3126 ISO Abbreviation: Biol. Neonate Publication Date: 1992 |
Date Detail:
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Created Date: 1992-12-08 Completed Date: 1992-12-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0247551 Medline TA: Biol Neonate Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 155-63 Citation Subset: IM |
Affiliation:
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Department of Animal Science, Ohio State University, Columbus. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn / metabolism* Carrier Proteins / metabolism* Colostrum* DNA / metabolism Fatty Acid-Binding Proteins Fatty Acids / metabolism Intestinal Mucosa / metabolism Intestines / growth & development*, metabolism, ultrastructure Intubation, Gastrointestinal Microvilli / ultrastructure Milk* Neoplasm Proteins* Swine |
| Chemical | |
Reg. No./Substance:
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0/Carrier Proteins; 0/Fatty Acid-Binding Proteins; 0/Fatty Acids; 0/Neoplasm Proteins; 9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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