Document Detail


Intestinal cholesterol absorption.
MedLine Citation:
PMID:  10482134     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The strong association between intestinal cholesterol absorption and total plasma cholesterol level has renewed interest in the absorptive process and stimulated the generation of new animal models. Increasingly, new studies suggest that cholesterol absorption is genetically controlled and supports a protein-mediated mechanism for cholesterol uptake into the intestinal mucosal cell. Insights into potential mechanisms are predicted to lead to novel pharmacological approaches to inhibit cholesterol absorption.
Authors:
P A Dawson; L L Rudel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Current opinion in lipidology     Volume:  10     ISSN:  0957-9672     ISO Abbreviation:  Curr. Opin. Lipidol.     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-10-20     Completed Date:  1999-10-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9010000     Medline TA:  Curr Opin Lipidol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  315-20     Citation Subset:  IM    
Affiliation:
Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cholesterol / blood,  metabolism*
Humans
Intestinal Absorption / drug effects,  genetics,  physiology*
Primates
Grant Support
ID/Acronym/Agency:
DK 47987/DK/NIDDK NIH HHS; HL 24736/HL/NHLBI NIH HHS; HL 49373/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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