| Intestinal adaptation in short bowel syndrome. | |
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MedLine Citation:
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PMID: 12071459 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Regaining enteral autonomy after extensive small bowel resection is dependent on intestinal adaptation. This adaptational process is characterized by hyperplastic growth of the remaining gut, which is accompanied by both an increase of cell division at the level of the crypt cells and by an increased rate of programmed cell death (apoptosis). Apart from the absorptive function, the small bowel also has a barrier function and plays an important role in interorgan metabolism. Also, these functions are greatly affected by a massive intestinal resection and subsequent recovery by intestinal adaptation. This review aims to give an overview of the debilitating effects of massive intestinal resection on gut function and subsequently discusses intestinal adaptation and possible factors stimulating adaptation. |
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Authors:
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Carlo F M Welters; Cornelius H C Dejong; Nicolaas E P Deutz; Erik Heineman |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: ANZ journal of surgery Volume: 72 ISSN: 1445-1433 ISO Abbreviation: ANZ J Surg Publication Date: 2002 Mar |
Date Detail:
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Created Date: 2002-06-19 Completed Date: 2002-10-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 101086634 Medline TA: ANZ J Surg Country: Australia |
Other Details:
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Languages: eng Pagination: 229-36 Citation Subset: IM |
Affiliation:
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Department of Surgery, Academic Hospital and University of Maastricht, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological
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physiology* Humans Recovery of Function / physiology Short Bowel Syndrome / physiopathology*, rehabilitation* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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