Document Detail

Intestinal accumulation of 111In-granulocytes in patients studied because of occult infection.
MedLine Citation:
PMID:  3113959     Owner:  NLM     Status:  MEDLINE    
111In-granulocyte scintigraphy was performed on 245 patients in whom a localized infection was suspected. In 123 patients scintigraphy was positive and of these 35 (28%) had intestinal accumulations of 111In-granulocytes. Specific local causes for the intestinal uptake of radioactivity were antibiotic associated colitis (eight patients), local pyogenic bowel infection (four patients), systemic disease (two patients), bowel necrosis (two patients), colonic cancer (one patient) and Stevens-Johnson's syndrome (one patient). Nonspecific mechanisms of bowel accumulation were desquamation of labelled granulocytes (12 patients) and bleeding (two patients). In three cases the mechanism of colonic accumulation of granulocytes was not revealed. These results show that unexpected accumulations of labelled granulocytes in the gut is not a rare phenomenon and is often due to clinically significant intestinal inflammation or other disease, especially in patients who do not have signs of respiratory, pancreatic or oesophageal inflammation causing desquamated granulocytes to accumulate in the gut.
M T Syrjälä; K Liewendahl; V Valtonen; J Gripenberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of nuclear medicine     Volume:  13     ISSN:  0340-6997     ISO Abbreviation:  Eur J Nucl Med     Publication Date:  1987  
Date Detail:
Created Date:  1987-10-09     Completed Date:  1987-10-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7606882     Medline TA:  Eur J Nucl Med     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  121-4     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Bacterial Infections / radionuclide imaging*
Child, Preschool
Enteritis / radionuclide imaging*
Indium Radioisotopes / diagnostic use
Middle Aged
Organometallic Compounds / diagnostic use
Oxyquinoline / analogs & derivatives,  diagnostic use
Reg. No./Substance:
0/Indium Radioisotopes; 0/Organometallic Compounds; 14514-42-2/indium oxine; 148-24-3/Oxyquinoline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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