Document Detail

Intestinal absorption of dietary carotenoids.
MedLine Citation:
PMID:  17195263     Owner:  NLM     Status:  MEDLINE    
The assessment of carotenoid bioavailability has long been hampered by the limited knowledge of their absorption mechanisms. However, recent reports have elucidated important aspects of carotenoid digestion and absorption. Disruption of food matrix and increasing amounts of fat seem to enhance the absorption of carotenes to a larger extent than that of xanthophylls. Comparing different carotenoid species, xanthophylls seem to be more easily released from the food matrix and more efficiently micellized than the carotenes. On the other hand, carotenes are more efficiently taken up by the enterocytes. However, carotenoid emulsification and micellization steps are largely affected by the food matrix and dietary components, being the main determinant of carotenoid bioavailability from foodstuffs. Although the intestinal uptake of carotenoids has been thought to occur by simple diffusion, recent studies reported the existence of receptor-mediated transport of carotenoids in enterocytes. Comparisons between the intestinal absorption of a wide array of carotenoids would be useful to elucidate the absorption mechanism of each carotenoid species, in view of the recent indications that intestinal carotenoid uptake may involve the scavenger receptor class B type I and possibly other epithelial transporters. The unraveling of the whole mechanism underlying the absorption of carotenoids will be the challenge for future studies.
Lina Yonekura; Akihiko Nagao
Related Documents :
15145963 - Limited sampling strategy of s-warfarin concentrations, but not warfarin s/r ratios, ac...
3606933 - Food increases the bioavailability of propafenone.
15829683 - Derivation of sustainable breeding goals for dairy cattle using selection index theory.
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Molecular nutrition & food research     Volume:  51     ISSN:  1613-4125     ISO Abbreviation:  Mol Nutr Food Res     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-15     Completed Date:  2007-05-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231818     Medline TA:  Mol Nutr Food Res     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  107-15     Citation Subset:  IM    
National Food Research Institute, Tsukuba, Ibaraki, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Biological Transport
Carotenoids / administration & dosage,  pharmacokinetics*
Dietary Fiber / administration & dosage
Fatty Acids / administration & dosage
Intestinal Absorption*
Phytosterols / administration & dosage
Scavenger Receptors, Class B / physiology
Sucrose / administration & dosage,  analogs & derivatives
Reg. No./Substance:
0/Fatty Acids; 0/Phytosterols; 0/SCARB1 protein, human; 0/Scavenger Receptors, Class B; 121854-29-3/sucrose polyester; 36-88-4/Carotenoids; 57-50-1/Sucrose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Context is everything: Mining the normal and preneoplastic microenvironment for insights into the di...
Next Document:  IgE-mediated food allergy diagnosis: Current status and new perspectives.