Document Detail

Interventricular septum motion abnormalities: unexpected echocardiographic changes of Brugada syndrome.
MedLine Citation:
PMID:  18067763     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: There remains controversy about whether Brugada syndrome (BS) has structural heart changes. We occasionally noted that a patient with BS had a quite unusual regional wall motion abnormality at the basal segment of the interventricular septum (IVS) during echocardiographic examination. The unexpected finding promoted us to reexamine our patients with BS by echocardiographic interrogation in the present study. METHODS: Patients with BS (n = 11), patients with complete right bundle branch block (RBBB) (n = 11), and control subjects (n = 11) were enrolled in this study. Two-dimensional echocardiography (2DE) was performed to obtain parasternal left ventricular long axis view on which M-mode scanning line was adjusted to be perpendicular to the basal segment of IVS for delineation of the segmental motion curve, with a simultaneously electrocardiographic tracing. RESULTS: 2DE revealed a rapid swing motion shifting toward the right ventricle of the IVS basal segment at early systole in 73% (8/11) patients with BS, which was further confirmed on the M-mode curve evidenced by an early systolic notch toward the right ventricle. The position of the notch corresponded to C-point on the mitral motion curve, lasting for (53 +/- 5) ms. There were no similar changes both in patients with RBBB and in the control subjects. CONCLUSION: IVS basal motion abnormalities at early-systolic phase may be the novel finding of BS.
Zheng-rong Huang; Liang-long Chen; Wei-hua Li; Qi-zhu Tang; Cong-xin Huang; Qiang Xie; Gang Wu; Lin Fan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chinese medical journal     Volume:  120     ISSN:  0366-6999     ISO Abbreviation:  Chin. Med. J.     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-12-10     Completed Date:  2008-09-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7513795     Medline TA:  Chin Med J (Engl)     Country:  China    
Other Details:
Languages:  eng     Pagination:  1898-901     Citation Subset:  IM    
Department of Cardiology, First Hospital of Xiamen, Fujian Medical University, Xiamen, China.
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MeSH Terms
Brugada Syndrome / pathology,  physiopathology,  ultrasonography*
Echocardiography / methods*
Middle Aged
Ventricular Septum / pathology*,  physiopathology

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