| Interventricular and intraventricular dyssynchrony are common in heart failure patients, regardless of QRS duration. | |
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MedLine Citation:
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PMID: 15120054 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: The study aimed at evaluating the prevalence of interventricular and intraventricular contractile dyssynchrony in heart failure patients with either normal or prolonged QRS duration. METHODS AND RESULTS: Echocardiography and tissue Doppler imaging (TDI) were performed in 158 consecutive patients with advanced left ventricular dysfunction (LVEF<35%); 61 patients had a normal QRS duration (Group 1), 21 patients had left bundle branch block with a QRS duration between 120 and 150 ms (Group 2) and 76 patients had a QRS duration #10878;150 ms (Group 3). Interventricular dyssynchrony (defined by the presence of an interventricular mechanical delay greater than 40 ms) was found in 12.5%, 52.4% and 72% of patients in Group 1, 2 and 3, respectively (p < 0.001). Intraventricular dyssynchrony (defined by the presence of one or more differences greater than 50 ms among regional pre-ejection periods) was observed in 29.5%, 57.1% and 71% of patients in Group 1, 2 and 3, respectively (p < 0.001). No relationship was found between interventricular and intraventricular dyssynchrony. CONCLUSIONS: A substantial proportion of heart failure patients with a slightly prolonged QRS or even with normal conduction may exhibit ventricular dyssynchrony. Both standard echocardiography and TDI are necessary to describe the entire spectrum of mechanical abnormalities due to dyssynchrony. |
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Authors:
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Stefano Ghio; Cristina Constantin; Catherine Klersy; Alessandra Serio; Alessandra Fontana; Carlo Campana; Luigi Tavazzi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European heart journal Volume: 25 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 2004 Apr |
Date Detail:
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Created Date: 2004-05-03 Completed Date: 2004-07-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: England |
Other Details:
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Languages: eng Pagination: 571-8 Citation Subset: IM |
Affiliation:
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Division of Cardiology, IRCCS Policlinico San Matteo Hospital, Pavia, Italy. s.ghio@smatteo.pv.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Echocardiography, Doppler, Color
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methods Electrocardiography / methods Female Heart Block / etiology*, physiopathology Heart Failure / etiology*, physiopathology Humans Male Middle Aged Ventricular Dysfunction, Left / etiology*, physiopathology |
| Comments/Corrections | |
Comment In:
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Eur Heart J. 2004 Aug;25(15):1363; author reply 1363-4
[PMID:
15288163
]
Eur Heart J. 2004 Apr;25(7):535-6 [PMID: 15120047 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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