Document Detail

Interventions to prevent hypothermia at birth in preterm and/or low birthweight infants.
MedLine Citation:
PMID:  20238329     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Keeping vulnerable preterm infants warm is problematic even when recommended routine thermal care guidelines are followed in the delivery suite.
OBJECTIVES: To assess efficacy and safety of interventions designed for prevention of hypothermia in preterm and/or low birthweight infants applied within 10 minutes after birth in the delivery suite compared with routine thermal care.
SEARCH STRATEGY: We used the standard search strategy of the Cochrane Neonatal Review Group (CNRG). The review was updated in October 2009.
SELECTION CRITERIA: Trials using randomised or quasi-randomised allocations to test a specific intervention designed to prevent hypothermia, (apart from 'routine' thermal care) applied within 10 minutes after birth in the delivery suite to infants of < 37 weeks' gestational age or birthweight </= 2500 g.
DATA COLLECTION AND ANALYSIS: We used the methods of the CNRG for data collection and analysis.
MAIN RESULTS: 1) Barriers to heat loss [5 studies; plastic wrap or bag (3), plastic cap (1), stockinet cap (1)]:Plastic wraps or bags were effective in reducing heat losses in infants < 28 weeks' gestation (4 studies, n = 223; WMD 0.68 degrees C; 95% CI 0.45, 0.91), but not in infants between 28 to 31 week's gestation. Plastic caps were effective in reducing heat losses in infants < 29 weeks' gestation (1 study, n = 64; MD 0.80 degrees C; 95% CI 0.41, 1.19). There was insufficient evidence to suggest that either plastic wraps or plastic caps reduce the risk of death within hospital stay. There was no evidence of significant differences in other clinical outcomes for either the plastic wrap/bag or the plastic cap comparisons. Stockinet caps were not effective in reducing heat losses.2) External heat sources [2 studies; skin-to-skin (1), transwarmer mattress (1)]:Skin-to-skin care (SSC) was shown to be effective in reducing the risk of hypothermia when compared to conventional incubator care for infants (1 study, n = 31; RR 0.09; 95% CI 0.01, 0.64). The transwarmer mattress reduced the incidence of hypothermia on admission to NICU in VLBW infants (1 study, n = 24; RR 0.30; 95% CI 0.11, 0.83).
AUTHORS' CONCLUSIONS: Plastic wraps or bags, plastic caps, SSC and transwarmer mattresses all keep preterm infants warmer leading to higher temperatures on admission to neonatal units and less hypothermia. However, the small numbers of infants and studies and the absence of long-term follow-up mean that firm recommendations for clinical practice cannot be given.
Emma M McCall; Fiona Alderdice; Henry L Halliday; John G Jenkins; Sunita Vohra
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Publication Detail:
Type:  Journal Article; Meta-Analysis; Review     Date:  2010-03-17
Journal Detail:
Title:  The Cochrane database of systematic reviews     Volume:  -     ISSN:  1469-493X     ISO Abbreviation:  Cochrane Database Syst Rev     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-18     Completed Date:  2010-04-26     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  100909747     Medline TA:  Cochrane Database Syst Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  CD004210     Citation Subset:  IM    
School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, Microbiology Building, Grosvenor Road, Belfast, Northern Ireland, UK, BT12 6BN.
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MeSH Terms
Hypothermia / prevention & control*
Infant, Low Birth Weight*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / prevention & control*
Perinatal Care / methods
Randomized Controlled Trials as Topic
Update Of:
Cochrane Database Syst Rev. 2008;(1):CD004210   [PMID:  18254039 ]

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