Document Detail

Interventions to improve the physical function of ICU survivors: a systematic review.
MedLine Citation:
PMID:  23949645     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: ICU admissions are ever increasing across the United States. Following critical illness, physical functioning (PF) may be impaired for up to 5 years. We performed a systematic review of randomized controlled trials evaluating the efficacy of interventions targeting PF among ICU survivors. The objective of this study was to identify effective interventions that improve long-term PF in ICU survivors.
METHODS: MEDLINE, Excerpta Medica Database (EMBASE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Physiotherapy Evidence-Based Database (PEDro) were searched between 1990 and 2012. Two reviewers independently evaluated studies for eligibility, critically appraised the included studies, and extracted data into standardized evidence tables.
RESULTS: Fourteen studies met the inclusion criteria. Interventions included exercise/physical therapy (PT), parenteral nutrition, nurse-led follow-up, spontaneous awakening trials, absence of sedation during mechanical ventilation, and early tracheotomy. Nine studies failed to demonstrate efficacy on PF of the ICU survivors. However, early physical exercise and PT-based interventions had a positive effect on long-term PF.
CONCLUSIONS: The only effective intervention to improve long-term PF in critically ill patients is exercise/PT; its benefit may be greater if started earlier. Further research in this area comparing different interventions and timing is needed.
Enrique Calvo-Ayala; Babar A Khan; Mark O Farber; E Wesley Ely; Malaz A Boustani
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Chest     Volume:  144     ISSN:  1931-3543     ISO Abbreviation:  Chest     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2013-11-06     Completed Date:  2014-01-09     Revised Date:  2014-11-10    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1469-80     Citation Subset:  AIM; IM    
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MeSH Terms
Critical Illness / therapy*
Exercise Therapy / methods*
Intensive Care Units*
Quality of Life
Grant Support
K23 AG043476/AG/NIA NIH HHS; R01 AG034205/AG/NIA NIH HHS

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