| Interventions for preventing occupational irritant hand dermatitis. | |
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MedLine Citation:
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PMID: 20556758 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Occupational irritant hand dermatitis (OIHD) is an important cause of discomfort in the working population. Different preventive measures are in place but it is not clear how effective these are. OBJECTIVES: To assess the effect of interventions for preventing OIHD in healthy people who work in occupations where the skin is at risk of damage. SEARCH STRATEGY: In May 2010, we searched the Cochrane Skin Group Specialised Register, the Cochrane Central Register of Controlled Trials in The Cochrane Library, MEDLlNE and EMBASE. Conference proceedings, and ongoing trials registers were also searched. SELECTION CRITERIA: Randomised controlled trials (RCTs) studying the effectiveness of barrier creams, moisturisers, gloves, complex educational interventions, and other interventions for the prevention of OIHD. DATA COLLECTION AND ANALYSIS: Two authors independently assessed the trials and extracted data. MAIN RESULTS: Four RCTs involving 894 participants from different occupations were included. The primary outcome was numbers of new cases.One large RCT of 708 print and dye workers compared 2 barrier creams (containing silicone or hydrocarbon) versus no intervention. Fewer workers using barrier creams developed OIHD than those who did not (39.9% versus 45%, (OR 0.75, 95% CI 0.53 to 1.07. P = 0.11) but this was not statistically significant.In 1 RCT of 54 metal workers less developed OIHD when using an after work emollient or a barrier cream compared to no intervention. There was no statistical difference between the groups at different times of follow-up.One RCT of 111 cleaners and kitchen workers compared a moisturiser (Locobase) versus no intervention using a cross-over design. While using the moisturiser no participant developed OIHD. During the control period with no skin treatment, 19 (20.4%) out of 93 participants developed OIHD.One RCT of 21 hairdressers compared a barrier cream containing aluminium chlorohydrate (Excipial protect) versus its vehicle. No participant developed OIHD while the products were used.Only limited side-effects such as transient itching, stinging, and dryness were reported for the interventions. AUTHORS' CONCLUSIONS: Although the findings of this review were generally positive, no statistical significance was reached. We conclude that at present there is insufficient evidence for the effectiveness of most of the interventions used in the primary prevention of OIHD. This does not mean that current measures are necessarily ineffective, as the limited studies to date have been rather small and of poor quality. Larger well designed RCTs are now needed in different workplaces to establish the effectiveness of various preventative strategies. |
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Authors:
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Andrea Bauer; Jochen Schmitt; Cathy Bennett; Pieter-Jan Coenraads; Peter Elsner; John English; Hywel C Williams |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-06-16 |
Journal Detail:
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Title: Cochrane database of systematic reviews (Online) Volume: - ISSN: 1469-493X ISO Abbreviation: Cochrane Database Syst Rev Publication Date: 2010 |
Date Detail:
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Created Date: 2010-06-17 Completed Date: 2010-07-27 Revised Date: 2011-01-03 |
Medline Journal Info:
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Nlm Unique ID: 100909747 Medline TA: Cochrane Database Syst Rev Country: England |
Other Details:
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Languages: eng Pagination: CD004414 Citation Subset: IM |
Affiliation:
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Department of Dermatology, University Hospital Carl Gustav Carus, Technical University Dresden, Fetscherstr. 74, Dresden, Germany, 01307. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Dermatitis, Irritant
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prevention & control* Dermatitis, Occupational / prevention & control* Emollients / administration & dosage* Excipients / administration & dosage Hand Dermatoses / prevention & control* Humans Organic Chemicals / administration & dosage Randomized Controlled Trials as Topic |
| Chemical | |
Reg. No./Substance:
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0/Emollients; 0/Excipients; 0/Organic Chemicals; 0/locobase |
| Comments/Corrections | |
Comment In:
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Evid Based Nurs. 2011 Jan;14(1):21-2
[PMID:
21163797
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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