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Interventional endovascular therapy: SPECT cerebral blood flow imaging compared with transcranial doppler monitoring of balloon angioplasty and intraarterial papaverine for cerebral vasospasm.
MedLine Citation:
PMID:  17895143     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The effects of interventional endovascular treatment of cerebral vasospasm with balloon angioplasty or papaverine infusion were evaluated by single-photon emission computed tomography (SPECT) and transcranial Doppler (TCD) in 44 patients whose cerebral vasospasm was refractory to medical management. SPECT revealed blood flow improvements in 42% of patients with papaverine treated vessels and 70% of patients with balloon angioplasty (P=.037). TCD correlated with SPECT in 71% of patients in the papaverine group and 73% of patients in the balloon angioplasty group. TCD showed 93% of segments improved by angioplasty, whereas 43% of segments were improved with papaverine (P<.001). Disagreements were largely represented by patients with TCD velocity improvements in which SPECT blood flow imaging was, unchanged or worsened. Balloon angioplasty seems superior to papaverine infusion for treatment of vasospasm. SPECT and TCD are complementary tests in the evaluation of vasospasm and effect of interventional therapy.
Authors:
D H Lewis; J Paul Elliott; D W Newell; J M Eskridge; H Richard Winn
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association     Volume:  8     ISSN:  1052-3057     ISO Abbreviation:  J Stroke Cerebrovasc Dis     Publication Date:    1999 Mar-Apr
Date Detail:
Created Date:  2007-09-26     Completed Date:  2009-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111633     Medline TA:  J Stroke Cerebrovasc Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  71-5     Citation Subset:  -    
Affiliation:
Department of Radiology Harborview Medical Center, University of Washington School of Medicine, Seattle, WA, USA.
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