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Interventional AVM therapy against epileptic seizures: Treatment between Scylla and Charybdis?
MedLine Citation:
PMID:  22764262     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Symptomatic epileptic seizures constitute a common neurologic complication in patients with arteriovenous malformations (AVMs). In many patients, a first-ever seizure may be the clinical index event leading to the diagnosis of an otherwise asymptomatic AVM. This scenario seems to be particularly frequent in young adults, while during childhood and beyond the age of 60, AVMs are less likely to be diagnosed based on seizures alone.(1) The occurrence of seizures is associated with neuroradiologic features such as lobar AVM location, large nidus size, arterial border zone topography, and the presence of superficial venous drainage.(2) For nonepileptic patients diagnosed with an unruptured AVM, the 5-year incidence of first-ever seizures on follow-up has been estimated around 8%, but this risk may increase to 23% if AVM rupture has occurred.(3).
Authors:
Christian Stapf
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-3
Journal Detail:
Title:  Neurology     Volume:  -     ISSN:  1526-632X     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the Department of Neurology and the French National Referral Center for Rare Vascular Diseases of the Eye and Brain (CERVCO), APHP, Hôpital Lariboisière, and Université Paris Diderot - Sorbonne Paris Cité, Paris, France.
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