| Intervention for the prevention and control of hypertension and atherosclerotic diseases: United States and international experience. | |
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MedLine Citation:
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PMID: 6367448 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intervention to control hypertension and prevent coronary heart disease was initially undertaken in the United States in the late 1950s. It was conducted along three lines: randomized controlled trials, community demonstration projects, and broad public health and medical care efforts involving both the general population and its high-risk strata. This article reviews findings from the United States trials, particularly those on the primary prevention of coronary heart disease by unifactorial means (such as fat-modified diet, serum cholesterol-lowering drugs, antihypertensive drug treatment) and by multifactorial interventions. Results of unifactorial and multifactorial trials are discussed with reference to the prevention of high blood pressure. Studies in the United States are compared with research abroad, and current research needs are reviewed together with the implications for medical practice and public health. The United States population as a whole has a large high-risk segment. Since the late 1950s, significant population-wide changes have occurred in life-styles (diet, smoking, exercise habits), and this is especially true of the more educated. The proportion of persons with detected, treated, and controlled high blood pressure has risen markedly in all population strata. Consequently, a favorable shift has occurred in the population distribution of the major established risk factors: "rich" diet, hypercholesterolemia, high blood pressure, and cigarette smoking. It can be reasonably inferred that the steady and marked declines in death rates in the United States from coronary heart disease, stroke, all cardiovascular diseases, and all causes since 1968 are related to reductions in these risk factors. |
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Authors:
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J Stamler; R Stamler |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: The American journal of medicine Volume: 76 ISSN: 0002-9343 ISO Abbreviation: Am. J. Med. Publication Date: 1984 Feb |
Date Detail:
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Created Date: 1984-03-30 Completed Date: 1984-03-30 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0267200 Medline TA: Am J Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 13-36 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Arteriosclerosis / epidemiology, prevention & control* Blood Pressure Clinical Trials as Topic Diet Female Humans Hypertension / prevention & control* Male Middle Aged Primary Prevention / methods* Smoking United States |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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