Document Detail

Intervention for infants with brain injury: results of a randomized controlled study.
MedLine Citation:
PMID:  17138264     Owner:  NLM     Status:  MEDLINE    
A randomized clinical trail (RCT) employed a 12-month individualized cognitive/sensorimotor stimulation program to look at the efficacy of the intervention on 62 infants with suspected brain injury. The control group infants received the State-funded follow-up program provided by the Los Angeles (LA) Regional Centers while the intervention group received intensive stimulation using the Curriculum and Monitoring System (CAMS) taught by public health nurses (PHNs). The developmental assessments and outcome measures were performed at 6, 12 and 18 months corrected age and included the Bayley motor and mental development, the Home, mother-infant interaction (Nursing Child Assessment Feeding Scale (NCAFS) and Nursing Child Assessment Teaching Scale (NCATS)), parental stress and social support. At 18 months, 43 infants remained in the study. The results indicate that the intervention had minimal positive effects on the Bayley mental and motor development scores of infants in the intervention group. Likewise, the intervention did not contribute to less stress or better mother-infant interaction at 12 or 18 months although there were significant differences in the NCAFS scores favoring the intervention group at 6 months. There was a significant trend, however, for the control group to have a significant decrease over time on the Bayley mental scores. Although the sample was not large and attrition was at 31%, this study provides further support to the minimal effects of stimulation and home intervention for infants with brain injury and who may have more significant factors contributing to their developmental outcome.
Lina Kurdahi Badr; Meena Garg; Meghna Kamath
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural     Date:  2005-08-31
Journal Detail:
Title:  Infant behavior & development     Volume:  29     ISSN:  1934-8800     ISO Abbreviation:  Infant Behav Dev     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-12-01     Completed Date:  2007-02-02     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  7806016     Medline TA:  Infant Behav Dev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  80-90     Citation Subset:  IM    
School of Nursing, 901 East Alosta Avenue, Azusa Pacific University, Azusa, CA 90095, USA.
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MeSH Terms
Brain Injuries / diagnosis,  physiopathology*,  psychology
Child Development*
Cognition Disorders / etiology
Home Care Services
Magnetic Resonance Imaging
Mental Processes / physiology
Motor Activity
Nervous System Diseases / etiology
Patient Selection
Social Support
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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