Document Detail


Interval immobilization technique for recognition toward a highly hydrophilic cyanobacterium toxin.
MedLine Citation:
PMID:  15171933     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A novel adsorption medium containing selective molecular recognition site for one of the powerful cyanobacterium toxins, Cylindrospermopsin (CYN) was developed using a special technique, namely interval immobilization technique. The adsorption medium was prepared using molecular assembly derived from an alternative-template molecule coupled with functional monomers for fixing the interval between the ionic functional groups in CYN. As results of liquid chromatographic evaluations, selective molecular recognition ability for CYN was observed as expected. Further studies proved that the association constant for CYN on this medium was slightly higher than that on blank polymer.
Authors:
Takuya Kubo; Ken Hosoya; Yoshiyuki Watabe; Nobuo Tanaka; Hiroo Takagi; Tomoharu Sano; Kunimitsu Kaya
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences     Volume:  806     ISSN:  1570-0232     ISO Abbreviation:  J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-06-02     Completed Date:  2005-02-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101139554     Medline TA:  J Chromatogr B Analyt Technol Biomed Life Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  229-35     Citation Subset:  IM    
Affiliation:
Department of Polymer Science and Engineering, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adsorption
Bacterial Toxins / chemistry*
Chromatography, High Pressure Liquid
Cyanobacteria / chemistry*
Sensitivity and Specificity
Spectroscopy, Fourier Transform Infrared
Chemical
Reg. No./Substance:
0/Bacterial Toxins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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