Document Detail

Interval double transfer improves treatment success in patients with repeated IVF/ET failures.
MedLine Citation:
PMID:  18704673     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To examine whether double transfer of embryos on day 2-3 and on day 5 after ovum pick-up (OPU) improves IVF/ET success rates in patients with multiple consecutive IVF failures METHODS: Consecutive IVF failures patients (7.6 +/- 0.5) undergoing IVF/ET cycles were treated with interval double transfer on day 2-3 and on day 5 after OPU. Matched patients, that had embryos transferred only once on day 2 or 3 served as controls. RESULTS: Baseline and cycle characteristics were similar in the study group and controls. The total pregnancy rate was 44.6% in the study group and 24.2% in the controls (p = 0.001), and the clinical pregnancy rates were 38.5% and 19.6%, respectively (p = 0.001). CONCLUSIONS: Patients with multiple consecutive IVF/ET failures, treated with the interval double transfer approach had significantly improved cycle success rates compared with regular day 2 or 3 embryo transfer protocol.
B Almog; I Levin; I Wagman; R Kapustiansky; T Schwartz; N Mey-Raz; A Amit; F Azem
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Publication Detail:
Type:  Journal Article     Date:  2008-08-14
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  25     ISSN:  1058-0468     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-10-09     Completed Date:  2008-12-04     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  353-7     Citation Subset:  IM    
Sarah Racine IVF Unit, Lis Maternity Hospital, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
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MeSH Terms
Case-Control Studies
Embryo Implantation
Embryo Transfer / methods*
Fertilization in Vitro / methods*
Models, Statistical
Oocytes / cytology
Pregnancy Rate
Retrospective Studies
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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