Document Detail

Intertwin birth weight differences and conduct problems in early childhood.
MedLine Citation:
PMID:  20439797     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine whether twin birth weight differences relate to subsequent differences in conduct problems at 3 to 4 years of age. DESIGN: Retrospective cohort study using mothers' reports on twins' behavior, birth weight, and zygosity. A partial sample participated in laboratory visits. SETTING: Jerusalem, Israel. PARTICIPANTS: All ethnic Jewish families identified by the Israeli Ministry of the Interior as having twins born in 2004 and 2005 were sent mail surveys regarding children's development. Families of twins (n = 1319) answered the survey when the twins were 3 years old. Same-sex birth weight-discordant twin pairs (n = 112) were selected for the main analyses of the study. MAIN EXPOSURE: A birth weight difference of 20.0% or more between the twins. MAIN OUTCOME MEASURES: Mothers' reports on twins' conduct problems using the Strengths and Difficulties Questionnaire and difference in conduct problems between the lower and higher birth weight twins in birth weight-discordant twin pairs. RESULTS: In birth weight-discordant twin pairs, the twin with the higher birth weight was reported to have more conduct problems compared with the twin with the lower birth weight in 41.1% of twin pairs, whereas the twin with the lower birth weight was reported to have more conduct problems only in 20.5% of twin pairs. This effect tended to be stronger in dizygotic compared with monozygotic twins. CONCLUSIONS: The findings suggest an effect of birth weight differences on development of subsequent conduct problems. Further studies are needed to clarify the mediating factors of this effect. The results point to the importance of birth history for subsequent development.
David Mankuta; Ira Goldner; Ariel Knafo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of pediatrics & adolescent medicine     Volume:  164     ISSN:  1538-3628     ISO Abbreviation:  Arch Pediatr Adolesc Med     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-04     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9422751     Medline TA:  Arch Pediatr Adolesc Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  457-61     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Hadassah HebrewUniversity Hospital, Jerusalem, Israel.
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MeSH Terms
Analysis of Variance
Birth Weight*
Chi-Square Distribution
Child Behavior Disorders / epidemiology*
Child, Preschool
Infant, Newborn
Israel / epidemiology
Retrospective Studies
Twins, Dizygotic*
Twins, Monozygotic*

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