Document Detail

Interstitial pregnancy undetected during earlier first-trimester screening for fetal aneuploidy at 13 weeks' gestation.
MedLine Citation:
PMID:  18465810     Owner:  NLM     Status:  MEDLINE    
First-trimester screening for fetal aneuploidy using nuchal translucency (NT), pregnancy-associated plasma protein A, free or total beta-hCG, and maternal age constitutes a very effective screening test for fetal Down syndrome. We describe a case in which a patient presented at 14 weeks' gestation with an acute abdomen 1 week after first-trimester screening (including NT measurement) performed elsewhere, which was negative for trisomies 21 and 18. Sonographic examination revealed an interstitial pregnancy with a singleton fetus with present cardiac activity, which had not been noted 1 week earlier at the time of earlier transabdominal NT measurement. This case indicates that successful acquisition of a NT measurement during first-trimester screening for fetal aneuploidy does not negate the rare possibility of an unusual ectopic pregnancy.
David M Sherer; Mudar Dalloul; Margarita Sokolovski; Dorota Borawski; Freda Granderson; Ovadia Abulafia
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  37     ISSN:  1097-0096     ISO Abbreviation:  J Clin Ultrasound     Publication Date:    2009 Mar-Apr
Date Detail:
Created Date:  2009-03-16     Completed Date:  2009-07-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  168-70     Citation Subset:  IM    
Copyright Information:
2008 Wiley Periodicals, Inc.
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, State University of New York, Downstate Medical Center, 445 Lenox Road, Box 24, Brooklyn, NY 11203-2098, USA.
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MeSH Terms
Abdomen, Acute / etiology
Diagnostic Errors
Fallopian Tubes / surgery
Mass Screening / methods
Nuchal Translucency Measurement / methods
Pregnancy Trimester, First*
Pregnancy, Ectopic / diagnosis,  surgery,  ultrasonography*
Prenatal Diagnosis / methods*

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