Document Detail


Interstitial pregnancy treated by transcervical aspiration of the gestational sac combined with systemic and local administration of methotrexate.
MedLine Citation:
PMID:  21518136     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Interstitial pregnancy, which is a rare form of tubal ectopic pregnancy, can grow larger than those within the fallopian tube because the surrounding myometrium is more expandable than the tube; many cases are advanced and treated with surgical resection or a large amount of methotrexate (MTX). This report presents a case of an advanced interstitial pregnancy treated with systemic MTX and laparoscopic local MTX injection combined with transcervical aspiration of the gestational sac. A 27-year-old nulliparous female presented with an interstitial pregnancy. Serum human chorionic gonadotropin (hCG) level was 90 000 IU/L. MTX was given systemically (50 mg/m(2) i.m.) and the gestational sac was aspirated transcervically under laparoscopic guidance followed by local injection of 25 mg MTX. The patient received a total of only 95 mg MTX. The gestational sac disappeared and serum hCG became undetectable. The patient became pregnant spontaneously six months later, and delivered a live 2482-g infant in good condition by planned cesarean section at 36 weeks and 3 days of gestation. No defect of the myometrium was seen during the surgery. This therapy may be effective for interstitial pregnancy and can be performed safely with laparoscopy.
Authors:
Sousuke Kato; Tomohito Tanaka; Yoshito Terai; Yoshiki Yamashita; Masahide Ohmichi
Related Documents :
21277456 - Peripartum pulmonary embolism.
9252146 - Intrahepatic cholestasis of pregnancy: a french prospective study.
3761276 - Influence of the fetal pituitary-adrenal axis on fetal and maternal progesterone and un...
2845196 - Production of c21 steroids in rat fetal ovaries.
20860626 - Relationship between hyaluronic acid binding assay and outcome in art: a pilot study.
17882426 - Mr features of ectopic pregnancy.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-26
Journal Detail:
Title:  The journal of obstetrics and gynaecology research     Volume:  -     ISSN:  1341-8076     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9612761     Medline TA:  J Obstet Gynaecol Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 The Authors. Journal of Obstetrics and Gynaecology Research © 2011 Japan Society of Obstetrics and Gynecology.
Affiliation:
Department of Obstetrics and Gynecology, Osaka Medical College, Osaka, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Randomized controlled trial of different doses of metformin for ovulation induction in infertile wom...
Next Document:  Expression patterns of the steroid receptor coactivator family in human ovarian endometriosis.