Document Detail

Interstitial pneumonitis associated with "crack" cocaine abuse.
MedLine Citation:
PMID:  1914578     Owner:  NLM     Status:  MEDLINE    
A 33-year-old woman developed acute bilateral pulmonary infiltrates after the intense use of rock cocaine (crack). She subsequently had progressive deterioration of pulmonary function to the point of being ventilator-dependent. Open lung biopsy showed a chronic interstitial pneumonia with extensive accumulation of free silica within histiocytes associated with mild pulmonary fibrosis. This pattern of interstitial pneumonia has not been previously reported in crack users.
A E O'Donnell; F G Mappin; T J Sebo; H Tazelaar
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  100     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1991-11-15     Completed Date:  1991-11-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1155-7     Citation Subset:  AIM; IM    
Department of Medicine, Robert L. Thompson Strategic Hospital, Carswell AFB, Texas.
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MeSH Terms
Crack Cocaine / adverse effects*
Lung / pathology
Macrophages / pathology
Pulmonary Fibrosis / chemically induced*,  diagnosis
Silicosis / etiology,  pathology
Substance-Related Disorders / complications*
Reg. No./Substance:
0/Crack Cocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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