Document Detail


Interstitial fluid pressure in normal and inflamed pulp.
MedLine Citation:
PMID:  10759412     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Tissue pressure is the hydrostatic pressure in the interstitial fluid which surrounds the pulpal cells. This pressure outside the vessels is normally considerably lower than the blood pressure inside the vessels. The dental pulp has a relatively low interstitial compliance due to its enclosure between rigid dentin walls. Accordingly, even a modest increase in pulpal fluid volume will raise the tissue pressure, which may compress blood vessels, leading to ischemia and necrosis. Inflammation may lead to an increase in both interstitial fluid volume and blood volume in the low-compliant pulp and thereby increase the tissue pressure. However, the increased tissue pressure may, in turn, initiate increased lymph flow and absorption of fluid into capillaries in nearby non-inflamed tissue. Both of these latter factors will transport fluid out of the affected area and subsequently out of the tooth and consequently lower the tissue pressure. Increased tissue pressure, whether caused by increased blood volume or increased capillary filtration, will promote outward flow of fluid through exposed dentin tubules and thereby help to protect the pulp against entry of harmful substances. It seems physiologically beneficial, therefore, for the pulp to have a high tissue pressure, which promptly increases when blood flow increases due to its low compliance.
Authors:
K J Heyeraas; E Berggreen
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists     Volume:  10     ISSN:  1045-4411     ISO Abbreviation:  Crit. Rev. Oral Biol. Med.     Publication Date:  1999  
Date Detail:
Created Date:  2000-04-25     Completed Date:  2000-04-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9009999     Medline TA:  Crit Rev Oral Biol Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  328-36     Citation Subset:  D; IM    
Affiliation:
Department of Physiology, University of Bergen, Norway.
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MeSH Terms
Descriptor/Qualifier:
Absorption
Blood Pressure / physiology
Blood Volume / physiology
Capillaries / physiology
Dental Pulp / blood supply,  cytology,  physiology*
Dental Pulp Necrosis / etiology
Dentin / anatomy & histology
Extracellular Space / physiology*
Humans
Hydrostatic Pressure
Ischemia / etiology
Lymph / physiology
Pressure
Pulpitis / pathology,  physiopathology*
Regional Blood Flow / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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