Document Detail


Interstitial deletion of the distal long arm of chromosome 4, del (4)(q33-q35), in association with paternal balanced translocation.
MedLine Citation:
PMID:  19037546     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Interstitial deletions of the long arm of chromosome 4 are rare. The deletions may occur at the proximal or the distal portions of the chromosome and different breakpoints may be involved. We report an interstitial deletion of 4q: 46XY der 4 (q28;q35) in a six-year-old boy with dysmorphic features associated with moderate mental retardation. Parental chromosomal analysis showed a balanced paternal translocation.
Authors:
R Mdzin; C Ko; Z Abdul Latif; Z Zakaria
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Singapore medical journal     Volume:  49     ISSN:  0037-5675     ISO Abbreviation:  Singapore Med J     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-11-27     Completed Date:  2009-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404516     Medline TA:  Singapore Med J     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  e336-9     Citation Subset:  IM    
Affiliation:
Department of Pathology, Faculty of Medicine, Hospital Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Cheras, Kuala Lumpur, Malaysia. ayureena@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / genetics
Body Height
Child
Chromosome Banding
Chromosome Deletion*
Chromosome Disorders / genetics
Chromosomes, Human, Pair 4*
Fathers
Female
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Male
Mental Retardation / genetics
Translocation, Genetic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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