Document Detail

Interstitial cystitis with plasma cell bladder infiltration: case report and literature review.
MedLine Citation:
PMID:  20812539     Owner:  NLM     Status:  MEDLINE    
We report the case of a 76 ys-old woman with overactive bladder syndrome, determined by an histological exam of interstitial cystitis with plasma cell infiltration. To the best of our knowledge, in literature only a similar case has been described. The patient has been treated with corticosteroid therapy allowing a transitory benefit; despite this fact, after side effects have been shown, this therapy has been interrupted leading to the worsening of the previous sintomatology. Therefore the patient has undergone to radical cystectomy with orthotopic ileal neobladder. The phlogistic infiltration of the bladder wall is represented by the plasma cells for over 90% of the whole population. In addition, blood specimen was positive for perinuclear antineutrophil cytoplasmic antibodies (p-ANCA). All these elements could hint at a chronic cystitis due to autoimmune aetiology.
Mauro Pacella; Virginia Varca; Fabio Venzano; Carlo Toncini; Giorgio Carmignani; Alchiede Simonato
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Archivio italiano di urologia, andrologia : organo ufficiale [di] Società italiana di ecografia urologica e nefrologica / Associazione ricerche in urologia     Volume:  82     ISSN:  1124-3562     ISO Abbreviation:  Arch Ital Urol Androl     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-09-03     Completed Date:  2010-10-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9308247     Medline TA:  Arch Ital Urol Androl     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  122-4     Citation Subset:  IM    
"Luciano Giuliani" Department of Urology, University of Genoa, Genoa, Italy.
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MeSH Terms
Cystitis, Interstitial / pathology*
Plasma Cells*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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