| Interstitial cells of blood vessels. | |
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MedLine Citation:
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PMID: 20563538 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Blood vessels are made up of several distinct cell types. Although it was originally thought that the tunica media of blood vessels was composed of a homogeneous population of fully differentiated smooth muscle cells, more recent data suggest the existence of multiple smooth muscle cell subpopulations in the vascular wall. One of the cell types contributing to this heterogeneity is the novel, irregularly shaped, noncontractile cell with thin processes, termed interstitial cell, found in the tunica media of both veins and arteries. While the principal role of interstitial cells in veins seems to be pacemaking, the role of arterial interstitial cells is less clear. This review summarises the knowledge of the functional and structural properties of vascular interstitial cells accumulated so far, offers hypotheses on their physiological role, and proposes directions for future research. |
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Authors:
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Vladimír Pucovský |
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Publication Detail:
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Type: Journal Article; Review Date: 2010-06-16 |
Journal Detail:
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Title: TheScientificWorldJournal Volume: 10 ISSN: 1537-744X ISO Abbreviation: ScientificWorldJournal Publication Date: 2010 |
Date Detail:
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Created Date: 2010-06-21 Completed Date: 2010-08-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101131163 Medline TA: ScientificWorldJournal Country: England |
Other Details:
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Languages: eng Pagination: 1152-68 Citation Subset: IM |
Affiliation:
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Centre for Vision and Vascular Science, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast. v.pucovsky@qub.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Vessels / cytology* Humans Immunohistochemistry Muscle, Smooth, Vascular / cytology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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