| Interstitial K(+) in human skeletal muscle during and after dynamic graded exercise determined by microdialysis. | |
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MedLine Citation:
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PMID: 10666141 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Interstitial K(+) concentrations were measured during one-legged knee-extensor exercise by use of microdialysis with probes inserted in the vastus lateralis muscle of the subjects. K(+) in the dialysate was measured either by flame photometry or a K(+)-sensitive electrode placed in the perfusion outlet. The correction for fractional K(+) recovery was based on the assumption of identical fractional thallium loss. The interstitial K(+) was 4. 19 +/- 0.09 mM at rest and increased to 6.17 +/- 0.19, 7.48 +/- 1.18, and 9.04 +/- 0.74 mM at 10, 30, and 50 W exercise, respectively. The individual probes demonstrated large variations in interstitial K(+), and values >10 mM were obtained. The observed interstitial K(+) was markedly higher than previously found for venous K(+) concentrations at similar work intensities. The present data support a potential role for interstitial K(+) in regulation of blood flow and development of fatigue. |
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Authors:
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C Juel; H Pilegaard; J J Nielsen; J Bangsbo |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of physiology. Regulatory, integrative and comparative physiology Volume: 278 ISSN: 0363-6119 ISO Abbreviation: Am. J. Physiol. Regul. Integr. Comp. Physiol. Publication Date: 2000 Feb |
Date Detail:
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Created Date: 2000-04-07 Completed Date: 2000-04-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100901230 Medline TA: Am J Physiol Regul Integr Comp Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: R400-6 Citation Subset: IM; S |
Affiliation:
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Copenhagen Muscle Research Centre, August Krogh Institute, University of Copenhagen, DK-2100 Copenhagen, Denmark. cjuel@aki.ku.dk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Electrochemistry Exercise / physiology* Extracellular Space / metabolism* Humans Leg Male Microdialysis Muscle, Skeletal / metabolism* Photometry Potassium / metabolism* Range of Motion, Articular |
| Chemical | |
Reg. No./Substance:
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7440-09-7/Potassium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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