Document Detail


Interstitial Doppler optical coherence tomography.
MedLine Citation:
PMID:  16092347     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Doppler optical coherence tomography (OCT) can image tissue structure and blood flow at micrometer-scale resolution but has limited imaging depth. We report a novel, linear-scanning, needle-based Doppler OCT system using angle-polished gradient-index or ball-lensed fibers. A prototype system with a 19-guage (diameter of approximately 0.9 mm) echogenic needle is constructed and demonstrates in vivo imaging of bidirectional blood flow in rat leg and abdominal cavity. To our knowledge, this is the first demonstration of Doppler OCT through a needle probe in interstitial applications to visualize deeply situated microcirculation.
Authors:
Victor X D Yang; You X Mao; Nigel Munce; Beau Standish; Walter Kucharczyk; Norman E Marcon; Brian C Wilson; I Alex Vitkin
Related Documents :
20725337 - Simultaneous measurement of two-point-spread functions at different locations across th...
15962667 - Screening for diabetic retinopathy in rural area using single-field, digital fundus ima...
19021397 - Live imaging of mammalian retina: rod outer segments are stained by conventional mitoch...
14740797 - Effectiveness and safety of screening for diabetic retinopathy with two nonmydriatic di...
6947267 - Computer-enhanced video microscopy: digitally processed microscope images can be produc...
24961277 - Preparation of mica supported lipid bilayers for high resolution optical microscopy ima...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Optics letters     Volume:  30     ISSN:  0146-9592     ISO Abbreviation:  Opt Lett     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2005-08-11     Completed Date:  2005-10-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7708433     Medline TA:  Opt Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1791-3     Citation Subset:  IM    
Affiliation:
University Health Network, Toronto, Ontario, Canada. victor.yang@utoronto.ca
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Blood Flow Velocity / physiology
Echocardiography, Doppler / instrumentation*,  methods
Equipment Design
Equipment Failure Analysis
Feasibility Studies
Image Enhancement / instrumentation*
Microcirculation / physiology*,  ultrasonography*
Rats
Tomography, Optical Coherence / instrumentation*,  methods
Ultrasonography, Interventional / instrumentation*,  methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Resonance-temperature-insensitive phase-shifted long-period fiber gratings induced by surface deform...
Next Document:  Optical levitation and manipulation of stuck particles with pulsed optical tweezers.