Document Detail


Interstitial 9q- deletions in hematologic malignancies.
MedLine Citation:
PMID:  6744226     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sixteen patients with interstitial deletions of the long arm of chromosome #9 (9q-). were studied. From our observations and the findings of ten other cases in the literature, it can be deduced that the anomaly is almost exclusively found in myeloproliferative disorders and that it rarely occurs as the sole anomaly; however, in more than one-third of the cases, it was associated with a t(8;21) and occurred as a secondary event. The deletion appears to be interstitial, the breakpoints are somewhat variable, and the region carrying the abl oncogene was never involved.
Authors:
C Mecucci; K Vermaelen; G Kulling; J L Michaux; L Noens; W Van Hove; G Tricot; A Louwagie; H Van den Berghe
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cancer genetics and cytogenetics     Volume:  12     ISSN:  0165-4608     ISO Abbreviation:  Cancer Genet. Cytogenet.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-08-30     Completed Date:  1984-08-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7909240     Medline TA:  Cancer Genet Cytogenet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  309-19     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adolescent
Adult
Aged
Chromosome Deletion*
Chromosomes, Human, 21-22 and Y
Chromosomes, Human, 6-12 and X*
Female
Hematologic Diseases / genetics*
Humans
Karyotyping
Leukemia / genetics*
Lymphoma / genetics*
Male
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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