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Interspecies competition and inhibition within the oral microbial flora: environmental factors influence the inhibition of Streptococcus mutans by Streptococcus oligofermentans.
MedLine Citation:
PMID:  22607333     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Liu Y, Wu L, Wu F, Chu L, Liu X, Xia K, Wang Y. Interspecies competition and inhibition within the oral microbial flora: environmental factors influence the inhibition of Streptococcus mutans by Streptococcus oligofermentans. Eur J Oral Sci 2012; 120: 179-184. © 2012 Eur J Oral Sci Dental caries is a bacterial infectious disease. Streptococcus mutans is the primary pathogen that causes dental caries. Streptococcus oligofermentans is a new oral streptococcal species that can inhibit the growth of S. mutans specifically. The study aimed to assess the inhibition of S. mutans by S. oligofermentans under different oral environmental conditions. The inhibition under different carbohydrate and oxygen conditions was investigated in vitro using an interspecies interaction assay. The 4-aminoantipyine (4-ATTP) method was used to measure the yield and the initial production rate of H(2) O(2) in S. oligofermentans. The inhibitory effect was enhanced when the bacteria were cultured with carbohydrates and under aerobic conditions, or when S. oligofermentans was inoculated earlier than S. mutans. The initial synthesis rates of H(2) O(2) by S. oligofermentans were higher in the presence of carbohydrates and in aerobic culture conditions. In terms of the total H(2) O(2) yield, the effect of the environmental conditions was as follows: no carbohydrates > sucrose > glucose, and aerobic conditions > anaerobic conditions. We conclude that the presence of carbohydrate and oxygen significantly affect the ability of S. oligofermentans to inhibit the growth of S. mutans. The difference in inhibitory effect may be attributed to changes in the capacity of S. oligofermentans to produce H(2) O(2) .
Authors:
Ying Liu; Ligeng Wu; Fei Wu; Lei Chu; Xinxin Liu; Keke Xia; Yinghui Wang
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Publication Detail:
Type:  Journal Article     Date:  2012-04-21
Journal Detail:
Title:  European journal of oral sciences     Volume:  120     ISSN:  1600-0722     ISO Abbreviation:  Eur. J. Oral Sci.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504563     Medline TA:  Eur J Oral Sci     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  179-84     Citation Subset:  D; IM    
Copyright Information:
© 2012 Eur J Oral Sci.
Affiliation:
Department of Endodontics, School of Stomatology, Tianjin Medical University, Tianjin Department of Endodontics, Second Hospital of Shanxi Medical University, Shanxi Department of Paediatrics, School of Stomatology, Wenzhou Medical College, Zhejiang, China.
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