Document Detail


Intersection of autophagy with pathways of antigen presentation.
MedLine Citation:
PMID:  23136066     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Traditionally, macroautophagy (autophagy) is viewed as a pathway of cell survival. Autophagy ensures the elimination of damaged or unwanted cytosolic components and provides a source of cellular nutrients during periods of stress. Interestingly, autophagy can also directly intersect with, and impact, other major pathways of cellular function. Here, we will review the contribution of autophagy to pathways of antigen presentation. The autophagy machinery acts to modulate both MHCI and MHCII antigen presentation. As such autophagy is an important participant in pathways that elicit host cell immunity and the elimination of infectious pathogens.
Authors:
Natalie L Patterson; Justine D Mintern
Related Documents :
6191246 - Anti-mag igm antibodies in patients with neuropathy and igm m proteins: detection by el...
24532066 - New skin test for detection of bovine tuberculosis based on antigen-displaying polyeste...
1658646 - Invited review: motor neuropathies, motor neuron disorders, and antiglycolipid antibodies.
16600306 - Campylobacter coli enteritis and guillain-barré syndrome: no evidence of molecular mim...
3219236 - Htlv-1 infection in tropical spastic paraparesis: lymphocyte culture and serologic resp...
2401386 - Strategies in the development of human monoclonal antibodies.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2012-11-08
Journal Detail:
Title:  Protein & cell     Volume:  3     ISSN:  1674-8018     ISO Abbreviation:  Protein Cell     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-11     Completed Date:  2013-09-30     Revised Date:  2014-03-13    
Medline Journal Info:
Nlm Unique ID:  101532368     Medline TA:  Protein Cell     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  911-20     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Antigen Presentation*
Autophagy*
HLA Antigens / immunology
Humans
Thymus Gland / cytology,  immunology
Chemical
Reg. No./Substance:
0/HLA Antigens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A versatile building block: the structures and functions of negative-sense single-stranded RNA virus...
Next Document:  Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase...