Document Detail


Interrupted inferior vena cava in fetuses with omphalocele. Case series of fetuses referred for fetal echocardiography and review of the literature.
MedLine Citation:
PMID:  25460249     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES: Congenital heart disease is reported in 15-45% of omphalocele cases. Associated abnormalities of systemic veins have occasionally been reported in children and rarely documented in the fetus. We report a case series of interrupted inferior vena cava (Int-IVC) in association with omphalocele and review the literature.
METHODS: From our fetal database we identified all cases of omphalocele referred for fetal echocardiography (FE) between 1997 and 2012. We reviewed pre and postnatal medical records and performed a literature search from 1975 to present to identify previous relevant publications.
RESULTS: Of 9627 fetuses referred for FE, 34 had an omphalocele. Gestational age at FE was 17(+6) to 26(+4)weeks. Seven of the 34 fetuses were shown to have an Int-IVC with azygos continuation to a right-sided superior vena cava (SVC). The heart was structurally normal in all but one case. The abdominal wall defect was large and contained liver in all. There were three fetal demises and one neonatal death. Three cases were operated successfully. Since 1975, we identified 12 publications reporting omphalocele with systemic venous abnormalities. Abnormal IVC angulation may lead to surgical complications. Failure of IVC formation is likely to be a developmental rather than a situs abnormality. Int-IVC with a dilated azygos influences venous access and may predispose to venous thrombosis.
CONCLUSION: We have documented an association between large omphalocele and Int-IVC with azygos continuation to the SVC. In this small series, this did not have surgical implications. It will however, influence route of any future cardiac catheterisation and may have long-term implications.
Authors:
Elisabeth Mlczoch; Julene S Carvalho
Related Documents :
15255429 - Vancomycin therapy and the progression of methicillin-resistant staphylococcus aureus v...
8237349 - Vertebral aspergillosis. a case report and review of the literature.
20417809 - Hyperbaric oxygen therapy for chronic refractory osteomyelitis of the sternum.
12492759 - Decreased heroin availability in sydney in early 2001.
25206019 - Primary spinal primitive neuroectodermal tumour - a case report.
22334979 - Nephropathy in association with annular psoriasis.
8611199 - Paraganglioma of the cauda equina. a case report and review of the literature.
15763299 - Ectopic salivary tissue of the tonsil: a case report.
22540369 - A rare giant gastrointestinal stromal tumor of the stomach traversing the upper abdomen...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-22
Journal Detail:
Title:  Early human development     Volume:  91     ISSN:  1872-6232     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-12-2     Completed Date:  -     Revised Date:  2014-12-3    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-6     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Ltd. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Satellite cells from dystrophic muscle retain regenerative capacity.
Next Document:  Effect of gestation length on the levels of five innate defence proteins in human milk.