| Interrelationship between protein-energy malnutrition and essential fatty acid deficiency in nursing infants. | |
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MedLine Citation:
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PMID: 1899172 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The influence of severe protein-calorie malnutrition on essential fatty acid (EFA) status was evaluated in nursing infants aged 2-5 mo. A control group of the same age and with normal weight-for-height was also selected for this study. The fatty acid pattern of total phospholipids from plasma and red blood cells (RBCs) was determined and then used as a biochemical variable for evaluating EFA status. A sharp fall in the relative percentage of n-6 (omega-6) fatty acids concomitant with an increase in the n-9 fatty acids in plasma and RBC phospholipids was observed. These results are consistent with the picture of EFA deficiency and showed that the deficiency state is well correlated with the severity of malnutrition. Calculation of the product-precursor ratio of polyunsaturated fatty acids derived from linoleic acid (18:2n-6) in RBC phospholipids provides evidence for an impairment in the elongation-desaturation pathway promoted by the protein-calorie malnutrition. |
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Authors:
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M C Marín; M E De Tomás; O Mercuri; A Fernández; C T de Serres |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of clinical nutrition Volume: 53 ISSN: 0002-9165 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 1991 Feb |
Date Detail:
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Created Date: 1991-02-28 Completed Date: 1991-02-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 466-8 Citation Subset: AIM; IM |
Affiliation:
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Instituto de Investigaciones Bioquímicas de La Plata (INIBIOLP), CONICET-UNLP, Facultad de Ciencias Médicas, La Plata, Argentina. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Breast Feeding* Erythrocytes / metabolism Fatty Acids, Essential / blood, deficiency* Fatty Acids, Unsaturated / blood Female Humans Infant Infant, Newborn Male Phospholipids / blood Protein-Energy Malnutrition / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Essential; 0/Fatty Acids, Unsaturated; 0/Phospholipids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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