Document Detail


Interrelationship between glomerular filtration rate and renal transport of sodium and chloride during fetal life.
MedLine Citation:
PMID:  879240     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The maturation of the glomerular filtration rate (GFR) and the interrelationship between the GFR and the renal transport of sodium and chloride have been evaluated during the last trimester of gestation with the use of long-term experiments in fetal lambs. An increase in GFR (milliliters per minute) parallel to the increase in fetal body weight was demonstrated; however, no significant change was shown when the GFR (milliliters per minute per kilogram of fetal body weight) (1.141 +/- 0.079) was related to fetal body weight or gestational age. There was a constant increase in sodium and chloride reabsorption (microequivalents per minute) during the last third of gestation. This increase in sodium and chloride reabsorption was less than the increase in GFR (milliliters per minute) before 129 days but became higher than the rise of GFR (milliliters per minute) after 129 days of gestation.
Authors:
J E Robillard; C Sessions; R L Kennedey; L Hamel-Robillard; F G Smith
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  128     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-09-02     Completed Date:  1977-09-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  727-34     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Transport
Chlorides / metabolism*
Female
Fetus / physiology*
Glomerular Filtration Rate*
Kidney / embryology,  metabolism*
Pregnancy
Pregnancy Trimester, Third
Sheep
Sodium / metabolism*
Chemical
Reg. No./Substance:
0/Chlorides; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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