| Interpretive intra- and interobserver reproducibility of rest/stress 99Tcm-sestamibi myocardial perfusion SPECT in a consecutive group of male patients with stable angina pectoris before and after percutaneous transluminal angioplasty. | |
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MedLine Citation:
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PMID: 11388575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Observer variability of 99Tcm-sestamibi myocardial perfusion imaging (MPI) has rarely been investigated. The aim of our study was to evaluate the interpretive reproducibility with this technique. PATIENTS: We report on 108 consecutive male patients with stable angina pectoris, investigated before and after percutaneous transluminal angioplasty (PTCA). METHODS: A 2-day rest/stress 99Tcm-sestamibi gated single photon emission computed tomography (SPECT) protocol was used. MPI was interpreted by two independent observers without knowledge of clinical data, using a 20-segment scoring model. RESULTS: Intra- and interobserver agreement was found to be good to excellent (kappa = 0.71-0.85) with regard to the overall diagnosis as well as the individual vessel diagnosis (kappa = 0.60-0.87). However, agreement was higher for left anterior descending coronary artery (LAD) and left circumflex coronary artery (LCX) vascular territories than for the right coronary artery (RCA) territory. Moderate to good intraobserver agreement (kappa = 00.54-0.68) and slightly lower interobserver agreement (kappa = 0.52-0.56) was found for segmental score interpretation. When comparing the interpretive reproducibility before and after PTCA intra- and interobserver agreement was better after PTCA, probably reflecting the increase in normal scans after revascularization. CONCLUSIONS: In a group of consecutive male patients with stable angina pectoris interpretive reproducibility (overall and individual vessel diagnosis) was good to excellent. However, segmental scoring reproducibility was moderate to good. |
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Authors:
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A Johansen; A L Gaster; A Veje; P Thayssen; T Haghfelt; P F Hølund-Carlsen |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Nuclear medicine communications Volume: 22 ISSN: 0143-3636 ISO Abbreviation: Nucl Med Commun Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-06-04 Completed Date: 2001-11-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: England |
Other Details:
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Languages: eng Pagination: 531-7 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Odense University Hospital, Denmark. allan.johansen@dadlnet.dk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angina Pectoris / physiopathology, radionuclide imaging*, therapy* Exercise Test Factor IX* Follow-Up Studies Heart / physiopathology, radionuclide imaging* Humans Male Middle Aged Observer Variation Radiopharmaceuticals / diagnostic use* Reproducibility of Results Rest Technetium Tc 99m Sestamibi / diagnostic use* Tomography, Emission-Computed, Single-Photon* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 109581-73-9/Technetium Tc 99m Sestamibi; 9001-28-9/Factor IX |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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