Document Detail


Interpreting the carboxyhaemoglobin concentration in fetal cord blood.
MedLine Citation:
PMID:  2778293     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We calculated the fetal-to-maternal carboxyhaemoglobin concentration ratio in 19 mother-infant pairs at the time of term delivery. Mothers, who had a less than 10% drop in their carboxyhaemoglobin concentration during labour, had an average ratio of 1.40 +/- 0.19. For mothers whose carboxyhaemoglobin concentrations dropped by 10% or more during labour, the average fetal-to-maternal carboxyhaemoglobin concentration ratio was 1.83 +/- 0.48. There was a strong correlation (r = 0.82) between the percent change in maternal carboxyhaemoglobin concentration during labour and the fetal-to-maternal carboxyhaemoglobin concentration ratio at the time of delivery. We conclude that increased CO elimination during labour may be accompanied by rapid changes in the maternal carboxyhaemoglobin concentration, leading to a spuriously high fetal-to-maternal carboxyhemoglobin concentration ratio at the time of delivery.
Authors:
M B Leonard; H J Vreman; J E Ferguson; D W Smith; D K Stevenson
Related Documents :
15253483 - Elements in placenta and pregnancy outcome in arctic and subarctic areas.
11542953 - Sampling of prenatal and postnatal offspring from individual rat dams enhances animal u...
11982873 - Effects of child seats on the cardiorespiratory function of newborns.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of developmental physiology     Volume:  11     ISSN:  0141-9846     ISO Abbreviation:  J. Dev. Physiol.     Publication Date:  1989 Feb 
Date Detail:
Created Date:  1989-10-20     Completed Date:  1989-10-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7910737     Medline TA:  J Dev Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  73-6     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Stanford University School of Medicine, California 94305.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Carbon Monoxide / blood
Carboxyhemoglobin / analysis*
Female
Fetal Blood / analysis*
Humans
Hyperventilation / complications
Infant, Newborn
Labor, Obstetric
Maternal-Fetal Exchange*
Pregnancy
Smoking / blood
Grant Support
ID/Acronym/Agency:
HD-14426/HD/NICHD NIH HHS; RR-00081/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
630-08-0/Carbon Monoxide; 9061-29-4/Carboxyhemoglobin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Transferrin degradation by gastrointestinal fluids of suckling and weanling rats.
Next Document:  Influence of repeated exposure to rapidly developing hypoxaemia on the arousal and cardiopulmonary r...