Document Detail

Interpreting the Spine Patient Outcomes Research Trial. Medical vs surgical treatment of lumbar disk herniation: implications for future trials.
MedLine Citation:
PMID:  17708129     Owner:  NLM     Status:  MEDLINE    
The Spine Patient Outcomes Research Trial (SPORT) consisted of two parallel studies: an observational study and a randomized comparison of medical and surgical treatment of disk herniation. In the long-term, patients did well with either treatment, and an intention-to-treat analysis found no difference in outcomes. However, at 2 years 40% of patients in the surgical group of the randomized study still hadn't had surgery, and 40% of the medical patients did have surgery, muddying the results. Surgery was superior according to an analysis by the treatment patients actually received, but the study has been criticized for methodologic shortcomings, and the topic remains controversial.
Daniel Mazanec; Linda Okereke
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cleveland Clinic journal of medicine     Volume:  74     ISSN:  0891-1150     ISO Abbreviation:  Cleve Clin J Med     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-21     Completed Date:  2007-10-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8703441     Medline TA:  Cleve Clin J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  577-83     Citation Subset:  IM    
Center for Spine Health, Neurological Institute, Cleveland Clinic Foundation, OH 44195, USA.
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MeSH Terms
Evidence-Based Medicine*
Intervertebral Disk / injuries*,  surgery
Intervertebral Disk Displacement / drug therapy,  surgery*
Lumbar Vertebrae / injuries*,  surgery
Radiculopathy / drug therapy,  surgery*
Treatment Outcome*
Comment In:
Cleve Clin J Med. 2007 Aug;74(8):572, 575-6   [PMID:  17708128 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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