Document Detail

Interpretation of the TDx-FLM fluorescence polarization assay in pregnancies complicated by diabetes mellitus.
MedLine Citation:
PMID:  9259935     Owner:  NLM     Status:  MEDLINE    
The objective of this paper is to determine the applicability of the Abbott TDx-FLM fluorescence polarization assay in pregnancies complicated by diabetes mellitus. Retrospective review of records of women with pregnancies complicated by diabetes who underwent amniocentesis for fetal lung maturity using the Abbott TDx-FLM assay within 3 days of delivery was considered. Maternal diabetic control, neonatal birth weight, Apgar scores, umbilical cord gases, admissions to Neonatal Intensive Care Unit (NICU), development of respiratory distress syndrome (RDS) were evaluated. One hundred twenty-one patients with diabetes mellitus were identified. Thirteen (10.7%) had an FLM < or = 70 mg/g and 108 patients had > or = 70 mg/g. All obstetrical and diabetic variables were similar. RDS was not observed in neonates who had an FLM of > or = 70 mg/g. One neonate had RDS (FLM = 7.2 mg/g). The TDx-FLM > or = 70 mg/g may be interpreted as mature when obtained from transabdominal amniocentesis.
G O Del Valle; C D Adair; E E Ramos; F L Gaudier; L Sanchez-Ramos; R Morales
Related Documents :
12521455 - Maternal homocysteine levels and plasma lipids in gestational diabetes: is there any re...
17079565 - The impact of early nutrition in premature infants on later childhood insulin sensitivi...
20059445 - The hyperglycemia and adverse pregnancy outcome (hapo) study: can we use the results as...
3044115 - Fetal lung maturity in diabetic pregnancies: relation among amniotic fluid insulin, pro...
3286445 - Effect of insulin deficiency on low density lipoprotein metabolism in rabbits.
2863015 - The half-life of endogenous insulin and c-peptide in man assessed by somatostatin suppr...
Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study    
Journal Detail:
Title:  American journal of perinatology     Volume:  14     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-09-04     Completed Date:  1997-09-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  241-4     Citation Subset:  IM    
Regional Obstetric Consultants, Jacksonville, FL 32207, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Albumins / analysis*
Amniotic Fluid / chemistry*
Birth Weight
Fetal Organ Maturity*
Fluorescence Polarization Immunoassay / methods*
Gestational Age
Infant, Newborn
Lung / embryology
Phosphatidylglycerols / analysis*
Pregnancy Outcome
Pregnancy in Diabetics / complications*
Respiratory Distress Syndrome, Newborn / diagnosis*
Retrospective Studies
Sensitivity and Specificity
Reg. No./Substance:
0/Albumins; 0/Phosphatidylglycerols

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The efficacy of prophylactic erythromycin in preventing vertical transmission of Ureaplasma urealyti...
Next Document:  Cesarean deliveries at a university hospital: analysis of rates and indications.