| Interpregnancy interval and subsequent perinatal outcomes among women delaying initiation of childbearing. | |
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MedLine Citation:
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PMID: 19012690 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: While delayed initiation of childbearing is associated with adverse perinatal outcomes, whether or not risk persists and whether interpregnancy interval (IPI) affects the subsequent pregnancy remains unclear. Objectives: To examine second-pregnancy perinatal outcomes for women initiating childbearing age > or = 30 compared to those initiating childbearing aged 20-29, specifically examining the distribution of adverse perinatal outcomes, and their associations with the interpregnancy interval. METHODS: Retrospective cohort study using the Missouri maternally linked files 1978-1997. Perinatal outcomes included fetal death, low birthweight, preterm birth and small-for-gestational age. Predictor variables included maternal age at first pregnancy and IPI between the first and second pregnancy. RESULTS: With an increasing maternal age at first pregnancy, rates of very low birthweight (P = 0.0095), preterm delivery (P = 0.0126), moderately preterm (P = 0.0458), and extremely preterm (P = 0.0008) in the second pregnancy increased, while the rate of small-for-gestational age (P < 0.0001) declined. Interpregnancy intervals <6 and > or = 60 months were associated with a higher rate of adverse outcomes after controlling for maternal age at first pregnancy. Intervals of 12-17 months had the lowest rate of adverse outcomes for mothers 35+. Maternal age > or = 35 years at first pregnancy and IPI <6 months were independent risk factors for an adverse outcome in the second pregnancy, however no statistical interaction between these factors was observed. CONCLUSION: Delayed initiation of childbearing is associated with a persistent risk of adverse perinatal outcomes in the second pregnancy, with a short IPI contributing to this risk. As numbers of women delaying childbearing beyond age 30 increase, providers should consider these risks in counseling women about their reproductive plans. |
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Authors:
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Sarah K Nabukera; Martha S Wingate; Russell S Kirby; John Owen; Shailender Swaminathan; Greg R Alexander; Hamisu M Salihu |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The journal of obstetrics and gynaecology research Volume: 34 ISSN: 1341-8076 ISO Abbreviation: J. Obstet. Gynaecol. Res. Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-17 Completed Date: 2009-02-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9612761 Medline TA: J Obstet Gynaecol Res Country: Japan |
Other Details:
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Languages: eng Pagination: 941-7 Citation Subset: IM |
Affiliation:
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Department of Maternal and Child Health, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA. nabukera@uab.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Birth Intervals* Cohort Studies Female Humans Infant, Newborn Maternal Age* Middle Aged Pregnancy Pregnancy Outcome Reproductive Behavior* Retrospective Studies Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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