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International trends in the incidence of malignant melanoma 1953-2008 - are recent generations at higher or lower risk?
MedLine Citation:
PMID:  22532371     Owner:  NLM     Status:  Publisher    
The incidence of cutaneous malignant melanoma has steadily increased over the past 50 years in predominately fair-skinned populations. This increase is reported to have levelled off recently in several Northern and Western European countries, Australia and New Zealand and in North America. We studied the global patterns and time trends in incidence of melanoma by country and sex, with a focus on and age- and cohort-specific variations. We analysed the incidence data from 39 population-based cancer registries, examining all-ages and age-truncated standardised incidence rates of melanoma, estimating the annual percentage change and incidence rate ratios from age-period-cohort models. Incidence rates of melanoma continue to rise in most European countries (primarily Southern and Eastern Europe), whereas in Australia, New Zealand, the U.S., Canada, Israel and Norway, rates have become rather stable in recent years. Indications of a stabilisation or decreasing trend were observed mainly in the youngest age group (25-44 years). Rates have been rising steadily in generations born up to the end of the 1940s, followed by a stabilization or decline in rates for more recently-born cohorts in Australia, New Zealand, the U.S., Canada and Norway. In addition to the birth cohort effect, there was a suggestion of a period related influence on melanoma trends in certain populations. While our findings provide support that primary and secondary prevention can halt and reverse the observed increasing burden of melanoma, they also indicate that those prevention measures require further endorsement in many countries. © 2012 Wiley-Liss, Inc.
Friederike Erdmann; Joannie Lortet-Tieulent; Joachim Schüz; Hajo Zeeb; Rüdiger Greinert; Eckhard W Breitbart; Freddie Bray
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-24
Journal Detail:
Title:  International journal of cancer. Journal international du cancer     Volume:  -     ISSN:  1097-0215     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0042124     Medline TA:  Int J Cancer     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 UICC.
Section of Environment and Radiation, International Agency for Research on Cancer (IARC), 150 Cours Albert Thomas, 69372 Lyon, France; Association of Dermatological Prevention (ADP) e. V., Cremon 11, 20457 Hamburg, Germany; EUROSKIN e.V., Am Krankenhaus 1, 21614 Buxtehude, Germany.
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