Document Detail


International trends in asthma mortality.
MedLine Citation:
PMID:  9257010     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Throughout the 20th century many different patterns of asthma mortality have been observed. Following relatively stable asthma mortality rates during the first half of this century, there has been a gradual increase in asthma mortality in many countries over the last 50 years. Although a number of possible explanations have been proposed to explain this trend-including increases in asthma prevalence, increases in exposure to factors that trigger asthma attacks and changes in asthma management-their relative contribution in different countries is uncertain. Another pattern is that of sudden marked increases in asthma mortality occurring in at least seven countries in the 1960s and in New Zealand in the 1970s. Available evidence indicates that the cause of these 'epidemics' was the use of high dose preparations of two specific beta-agonist drugs, namely isoprenaline forte and fenoterol. The most recent trend observed in a number of western countries during the last decade has been a gradual reduction in asthma mortality; this may relate to improvements in the management of asthma.
Authors:
R Beasley; N Pearce; J Crane
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Ciba Foundation symposium     Volume:  206     ISSN:  0300-5208     ISO Abbreviation:  Ciba Found. Symp.     Publication Date:  1997  
Date Detail:
Created Date:  1997-10-15     Completed Date:  1997-10-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0356636     Medline TA:  Ciba Found Symp     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  140-50; discussion 150-6, 157-9     Citation Subset:  IM    
Affiliation:
Department of Medicine, Wellington School of Medicine, New Zealand.
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MeSH Terms
Descriptor/Qualifier:
Asthma / mortality*
Humans
New Zealand / epidemiology
World Health

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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