Document Detail


International air travel: a risk factor for attacks in acute intermittent porphyria.
MedLine Citation:
PMID:  12927685     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Five patients are reported with acute intermittent porphyria in whom attacks were apparently precipitated by international air travel. In four subjects this was the initial presenting attack and in a fifth the cause of an acute relapse in a patient requiring regular haem arginate prophylaxis. Multifactorial precipitants implicated include, dehydration, missed meals, alcohol use, infection, chronic hypoxia, premenstrual syndrome and stress. Acute intermittent porphyria should be suspected in individuals presenting with unexplained acute abdominal pain following international air travel. Appropriate precautions may reduce the incidence of attacks in known porphyrics.
Authors:
T J Peters; A C Deacon
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinica chimica acta; international journal of clinical chemistry     Volume:  335     ISSN:  0009-8981     ISO Abbreviation:  Clin. Chim. Acta     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-08-20     Completed Date:  2004-04-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1302422     Medline TA:  Clin Chim Acta     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  59-63     Citation Subset:  IM    
Affiliation:
Department of Clinical Biochemistry, King's College Hospital, Denmark Hill, London SE5 9RS, UK. timothy.peters@kcl.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Abdominal Pain
Adult
Aircraft
Arginine / therapeutic use
Female
Humans
Male
Porphyria, Acute Intermittent / diagnosis,  etiology*,  physiopathology
Travel*
Chemical
Reg. No./Substance:
74-79-3/Arginine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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