Document Detail

International Trends in Liver Cancer Incidence Rates.
MedLine Citation:
PMID:  21921256     Owner:  NLM     Status:  Publisher    
BACKGROUND: Several previous studies have documented region or country-specific liver cancer incidence trends around the world. However, no study has systematically examined the international pattern using the most recently updated incidence data from the International Agency for Research on Cancer. METHODS: We examined recent trends in liver cancer incidence rates from 1993-2002 by joinpoint analysis for 32 cancer registries worldwide using Cancer Incidence in Five Continents. We also examined the male to female rate ratios for these and four additional registries based on the 1998-2002 incidence data. RESULTS: Liver cancer incidence rates for both males and females statistically significantly increased from 1993-2002 for 8 of 32 cancer registries considered in the analysis. Increases were largely confined to economically developed countries of Western Europe, North America and Oceania. In contrast, rates decreased in both males and females in 5 registries including 3 in Asia. Despite this, the incidence rates in Asian countries are twice as high as those in Africa and over four times as high as rates in North America. Male to female rate ratios varied from 0.9 in Quito, Ecuador to 5.0 in France. CONCLUSIONS: Liver cancer incidence rates continue to increase in some low-risk parts of the world while they are decreasing in some of the highest risk countries in Asia. Etiologic studies are required to further elucidate factors contributing to the divergent liver cancer incidence trends worldwide. Impact: Our description of international liver cancer incidence trends may stimulate further etiologic studies.
Melissa M Center; Ahmedin Jemal
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-15
Journal Detail:
Title:  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology     Volume:  -     ISSN:  1538-7755     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200608     Medline TA:  Cancer Epidemiol Biomarkers Prev     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1Surveillance Research, American Cancer Society.
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