Document Detail


The International Database of Ambulatory Blood Pressure in relation to Cardiovascular Outcome (IDACO): protocol and research perspectives.
MedLine Citation:
PMID:  17760218     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The International Database on Ambulatory Blood Pressure Monitoring (1993-1994) lacked a prospective dimension. We are constructing a new resource of longitudinal population studies to investigate with great precision to what extent the ambulatory blood pressure improves risk stratification. METHODS: The acronym IDACO refers to the new International Database of Ambulatory blood pressure in relation to Cardiovascular Outcome. Eligible studies are population based, have fatal as well as nonfatal outcomes available for analysis, comply with ethical standards, and have been previously published in peer-reviewed journals. In a meta-analysis based on individual patient data, composite and cause-specific cardiovascular events will be related to various indexes derived by ambulatory blood pressure monitoring. The analyses will be stratified by cohort and adjusted for the conventional blood pressure and other cardiovascular risk factors. RESULTS: To date, the international database includes 7609 patients from four cohorts recruited in Copenhagen, Denmark (n=2311), Noorderkempen, Belgium (n=2542), Ohasama, Japan (n=1535), and Uppsala, Sweden (n=1221). In these four cohorts, during a total of 69,295 person-years of follow-up (median 9.3 years), 1026 patients died and 929 participants experienced a fatal or nonfatal cardiovascular event. Follow-up in five other eligible cohorts, involving a total of 4027 participants, is still in progress. We expect that this follow-up will be completed by the end of 2007. CONCLUSION: The international database of ambulatory blood pressure in relation to cardiovascular outcome will provide a shared resource to investigate risk stratification by ambulatory blood pressure monitoring to an extent not possible in any earlier individual study.
Authors:
Lutgarde Thijs; Tine W Hansen; Masahiro Kikuya; Kristina Björklund-Bodegård; Yan Li; Eamon Dolan; Valérie Tikhonoff; Jitka Seidlerová; Tatiana Kuznetsova; Katarzyna Stolarz; Manuel Bianchi; Tom Richart; Edoardo Casiglia; Sofia Malyutina; Jan Filipovsky; Kalina Kawecka-Jaszcz; Yuri Nikitin; Takayoshi Ohkubo; Edgardo Sandoya; Jiguang Wang; Christian Torp-Pedersen; Lars Lind; Hans Ibsen; Yutaka Imai; Jan A Staessen; Eoin O'Brien;
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Blood pressure monitoring     Volume:  12     ISSN:  1359-5237     ISO Abbreviation:  Blood Press Monit     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-30     Completed Date:  2007-09-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9606438     Medline TA:  Blood Press Monit     Country:  England    
Other Details:
Languages:  eng     Pagination:  255-62     Citation Subset:  IM    
Affiliation:
Studies Coordinating Centre, Department of Cardiovascular Diseases, University of Leuven, Leuven, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Belgium
Blood Pressure Monitoring, Ambulatory / statistics & numerical data*
Cardiovascular Diseases / etiology*,  mortality*
Cohort Studies
Databases, Factual / statistics & numerical data*
Denmark
Female
Follow-Up Studies
Humans
Hypertension / complications*,  epidemiology
Japan
Longitudinal Studies
Male
Meta-Analysis as Topic
Middle Aged
Risk Assessment
Sweden
Comments/Corrections
Comment In:
Blood Press Monit. 2007 Aug;12(4):243-4   [PMID:  17760215 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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