Document Detail


Internal carotid artery occlusion in a patient with malignant peritoneal mesothelioma: is it a sign of malignancy-related thrombosis?
MedLine Citation:
PMID:  10768615     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To our knowledge, the occlusion of arteries and platelet hyperaggregation have not been reported in patients with malignant mesothelioma. However, venous thromboembolism, especially in the pulmonary vasculature in association with thrombocytosis and hyperfibrinogenemia, are commonly noticed in this disorder. Furthermore, we detected enhanced platelet aggregation in a case of malignant peritoneal mesothelioma with internal carotid artery occlusion in whom there were postsplenectomy thrombocytosis and hyperfibrinogenemia. The possible mechanisms of ICA occlusion in this patient, including the role of MPM and postsplenectomy state, thrombocytosis, platelet functional changes, and other factors were investigated and discussed.
Authors:
Y Ustündağ; U Can; S Benli; Y Büyükasik; N Ozbek
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  319     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-05-04     Completed Date:  2000-05-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  265-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Gastroenterology, Başkent University School of Medicine, Ankara, Turkey. yucelu@baskent1.h.baskent.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Adult
Carotid Artery Thrombosis / etiology*,  radiography
Carotid Artery, Internal
Humans
Magnetic Resonance Imaging
Male
Mesothelioma / complications,  surgery*
Peritoneal Neoplasms / complications,  surgery*
Platelet Aggregation
Risk Factors
Splenectomy / adverse effects*
Thrombocytosis / complications*,  etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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